grief

Synonyms: affliction agony anguish bemoaning bereavement bewailing care dejection deploring depression desolation despair despondency discomfort disquiet distress dole dolor gloom grievance harassment heartache heartbreak infelicity lamentation lamenting malaise melancholy misery mortification mournfulness mourning pain purgatory regret remorse repining rue sadness sorrow torture trial tribulation trouble unhappiness vexation woe worry wretchedness

Antonyms: delight ecstasy exhilaration happiness