tire

Synonyms: annoy bore burn out bush collapse crawl debilitate deject depress disgust dishearten dispirit displease distress drain droop drop enervate ennui exasperate fag fail faint fatigue flag fold give out go stale grow weary harass irk irritate jade nauseate overburden overstrain overtax overwork pain pall peter out poop out prostrate put to sleep sap sicken sink strain tax vex weaken wear wear down wear out wilt worry yawn

Antonyms: activate energize fire up invigorate refresh