annihilate

Synonyms: abate abolish abrogate annul blot out crush decimate demolish do in eradicate erase expunge exterminate extinguish extirpate finish off invalidate liquidate massacre murder negate nullify obliterate quash quell raze root out rub out ruin slaughter take out undo vitiate wipe out wrack wreck

Antonyms: help preserve revive save